The KLI support international groups of scholars in the life and sustainability sciences working on interdisciplinary projects to conduct their groundbreaking research at the institute. KLI Focus Groups and Working Groups aim to develop ideas on a particular subject and generate suggestions for action. The participants have different scientific backgrounds and strive to develop specific, practical goals. Focus Groups are one-time meetings gathering and working together at the KLI for a period of one to maximum two weeks. Working Groups comprise 3 meetings over the course of one year and a half.
Prevailing scientific approaches study organisms largely as passive objects, predetermined in development by their genetic makeup, and in evolution by an external selective environment. Alternatively, organisms may be investigated as potential agents of adaptive phenotypes and evolutionary innovation by virtue of (previously evolved) repertoires of regulatory, developmental and behavioral response. Can biological phenomena such as flexible regulatory pathways, individual plasticity, and formative tissue interactions be understood as sources of organismic agency? How can we rigorously define this property, and how can it inform a robust scientific theory? What range of biological mechanisms comprise relevant research foci, and what changes to experimental approaches are suggested by an agency view? A shift in scientific emphasis to these complex, indeterminate response properties promises a more nuanced and complete understanding of biological systems than prevailing gene-based approaches. An agency focus also promises new avenues for investigating ecological resilience in the face of current environmental challenges on the one hand, and understanding and preventing human disease phenotypes, on the other. The proposed 31/2-day workshop will bring together evolutionary biologists (from multiple disciplines and study systems) as well as philosophers of biology to explore and critique biological agency as a research framework.
Outcomes will include identifying key strengths and weaknesses of a biological agency approach; formulating a broader research agenda for agency investigations; strengthening the conceptual framework for a science of agency, and building a research community joined by this focus. The primary output will be a dedicated special journal issue in either Evolution & Development or Journal of Experimental Zoology, both of which have previously expressed interest.