KLI Colloquia are invited research talks of about an hour followed by 30 min discussion. The talks are held in English, open to the public, and offered in hybrid format.
Fall-Winter 2025-2026 KLI Colloquium Series
Join Zoom Meeting
https://us02web.zoom.us/j/5881861923?omn=85945744831
Meeting ID: 588 186 1923
25 Sept 2025 (Thurs) 3-4:30 PM CET
A Dynamic Canvas Model of Butterfly and Moth Color Patterns
Richard Gawne (Nevada State Museum)
14 Oct 2025 (Tues) 3-4:30 PM CET
Vienna, the Laboratory of Modernity
Richard Cockett (The Economist)
23 Oct 2025 (Thurs) 3-4:30 PM CET
How Darwinian is Darwinian Enough? The Case of Evolution and the Origins of Life
Ludo Schoenmakers (KLI)
6 Nov (Thurs) 3-4:30 PM CET
Common Knowledge Considered as Cause and Effect of Behavioral Modernity
Ronald Planer (University of Wollongong)
20 Nov (Thurs) 3-4:30 PM CET
Rates of Evolution, Time Scaling, and the Decoupling of Micro- and Macroevolution
Thomas Hansen (University of Oslo)
4 Dec (Thurs) 3-4:30 PM CET
Chance, Necessity, and the Evolution of Evolvability
Cristina Villegas (KLI)
8 Jan 2026 (Thurs) 3-4:30 PM CET
Embodied Rationality: Normative and Evolutionary Foundations
Enrico Petracca (KLI)
15 Jan 2026 (Thurs) 3-4:30 PM CET
On Experimental Models of Developmental Plasticity and Evolutionary Novelty
Patricia Beldade (Lisbon University)
29 Jan 2026 (Thurs) 3-4:30 PM CET
Jan Baedke (Ruhr University Bochum)
Event Details
You are invited to a Zoom meeting.
18 April 2024 03:00 PM (CET)
https://univienna.zoom.us/j/69686475041?pwd=NUl6V0VBOGNtb0s4a0ZWd0RhdEtOdz09
Topic description / Abstract:
How has schizophrenia, a condition that significantly reduces an individual's evolutionary fitness, remained common across generations and cultures? Numerous theories about the evolution of schizophrenia have been proposed, most of which are not consistent with modern epidemiological and genetic evidence. I will briefly review this evidence and explore the cliff edge model of schizophrenia. It suggests that schizophrenia is the extreme manifestation of a polygenic trait or a combination of traits that, within a normal range of variation, confer cognitive, linguistic, and/or social advantages. Only beyond a certain threshold, these traits precipitate the onset of schizophrenia and reduce fitness. I provide the first mathematical model of this qualitative concept and show that it requires only very weak positive selection of the underlying trait(s) to explain today’s schizophrenia prevalence. This prediction, along with expectations about the effect size of schizophrenia risk alleles, are surprisingly well matched by empirical evidence. The cliff edge model predicts a dynamic change of selection of risk alleles, which explains the contradictory findings of evolutionary genetic studies.
Biographical note:
Philipp Mitteroecker is Professor at the Dept. of Evolutionary Biology at the University of Vienna and member of the Board of Directors of the Konrad Lorenz Institute for Evolution and Cognition Research since 2014. In 2024, he became President of the KLI. Philipp Mitteroecker is an expert in geometric morphometrics, the statistical analysis of biological form. More recently his work focuses on questions in Evolutionary Anthropology and Evolutionary Medicine.
